Bioassay Scientist II/III
Cellomatics Biosciences Ltd. is one of the UK’s fastest growing Contract Research Organisations (CRO) providing specialist pre-clinical laboratory services to support the drug development programmes of biotech and pharmaceutical companies.
Cellomatics Biosciences Ltd has an exciting opportunity for a highly motivated Bioassay Scientist II/III to join our operations in Nottingham, UK. The successful candidate will join a collaborative and dynamic team and report to the Bioassay Study Manager.
The ideal candidate will have a strong background in biological sciences with proven expertise in bioassay development and in vitro testing of therapeutic candidates, particularly using Transwell-based systems and advanced barrier models. This includes hands-on experience with models such as Caco-2, primary human keratinocytes, and primary bronchial epithelial cells cultured at air–liquid interface (ALI).
You will work in a highly collaborative, matrixed environment to design, execute, and interpret complex in vitro bioassays aligned with strategic project objectives, contributing to drug discovery and early clinical development programmes.
Job Responsibilities:
- Design, execute, and troubleshoot complex in vitro bioassays, including Transwell and barrier models
- Develop and optimise Transwell-based systems (e.g., permeability, transport, and barrier integrity assays)
- Perform laboratory work and prepare SOPs and COSHH documentation
- Analyse, interpret, and communicate scientific data (written and verbal)
- Present findings to internal and external stakeholders
- Lead method development, validation, transfer, and optimisation
- Troubleshoot experimental challenges and ensure delivery in line with client requirements
- Prepare high-quality scientific reports
- Maintain inventory of reagents and consumables
- Drive continuous improvements in quality, productivity, and innovation
- Support accreditation processes and client audits
- Contribute to business development and client interactions
- Develop training modules within area of expertise
- Support implementation of new equipment, systems, and processes
Qualifications and Essential Skills:
- PhD in Life Sciences or a related discipline, or MSc with at least 3 years of relevant research/CRO experience
- Strong hands-on experience in:
-Cell culture (primary cells and cell lines)
-Transwell systems and barrier models
-Air–liquid interface (ALI) cultures
-Specific experience with Caco-2 models, primary human keratinocytes, and primary bronchial epithelial cells
-2D and 3D functional assays
-Biochemical and molecular assays
-High-throughput screening
- Proven experience in developing and deploying assay systems
- Excellent communication and data presentation skills
- Strong analytical and problem-solving abilities
- Ability to work independently and collaboratively in a fast-paced environment
- Proactive, adaptable, and results-driven mindset
- Strong organisational and multitasking skills
- Proficiency in MS Office (Excel, Word, Outlook)
Location: 10 Colwick Quays Business Park, Road No 2, Colwick, NG4 2JY, Nottingham
Job Type: Full-time (37.5hrs per week)
Salary: Up to £36,000 per annum, depending on experience and skill set
Contract: Permanent
What we offer:
Our benefits package includes a competitive salary, discretionary performance related bonus annually, an initial 3% employer pension contribution, 24 days annual leave. This position is based at our facility at 10 Colwick Quays Business Park, Nottingham, UK.
To apply, please confirm your status of eligibility to work in the UK and send your CV with a covering letter outlining why you feel you would be suitable for this role to info@cellomaticsbio.com.
