Ophthalmology Bioassay Scientist / Senior Scientist
Cellomatics Biosciences Ltd. is one of the UK’s fastest growing Contract Research Organisations (CRO) providing specialist pre-clinical laboratory services to support the drug development programmes of biotech and pharmaceutical companies.
Cellomatics Biosciences Ltd has an exciting opportunity for an Ophthalmology Bioassay Scientist / Senior Scientist to join our operations in Nottingham, UK. The successful candidate will join a dynamic and collaborative team and report to the Bioassay Study Manager.
The ideal candidate will have a strong background in ophthalmology, ocular biology, or related life sciences, with expertise in developing advanced human-based translational models, including iPSC-derived systems and organoid models, for ocular diseases. You will work in a highly collaborative, matrixed environment to design, execute, and interpret complex in vitro bioassays supporting drug discovery and early clinical development.
Job Responsibilities:
- Develop and optimise in vitro ocular models, including corneal, retinal, and epithelial systems
- Design and implement iPSC-derived ocular models (e.g. retinal organoids, RPE models)
- Develop and characterise 3D organoid and co-culture systems to model ocular disease biology
- Design, execute, and analyse ocular disease-relevant bioassays (e.g. inflammation, barrier integrity, toxicity, efficacy)
- Perform laboratory work and prepare SOPs and COSHH documentation
- Analyse, interpret, and communicate scientific data (written and verbal)
- Present findings to internal and external stakeholders
- Lead method development, validation, transfer, and optimisation
- Troubleshoot experimental challenges and ensure project delivery to client requirements
- Prepare high-quality scientific reports
- Maintain inventory of reagents and consumables
- Drive continuous improvement in quality, productivity, and innovation
- Support accreditation processes and client audits
- Assist in business development and client interactions
- Develop training modules within area of expertise
- Support implementation of new equipment, systems, and processes
Qualifications and Essential Skills:
- PhD or MSc in Ophthalmology, Stem Cell Biology, Cell Biology, Molecular Biology, or a related discipline, with at least 3 years of relevant industry or CRO experience
- Strong experience in:
– Cell culture (primary cells and cell lines)
-iPSC culture, differentiation, and characterisation
-3D organoid development (e.g. retinal organoids, RPE systems)
-Ocular cell models (e.g. corneal epithelial cells, retinal cells, RPE cells)
-2D and 3D functional assays
-Barrier models and permeability assays
-Biochemical and molecular assays
-High-throughput screening
- Experience working with human-derived ocular cells, iPSC-derived systems, or organoids is highly desirable
- Demonstrated track record in assay development and translational model development
- Excellent communication and data presentation skills
- Strong analytical and problem-solving abilities
- Ability to work independently and collaboratively in a fast-paced environment
- Proactive, adaptable, and results-driven mindset
- Strong organisational and multitasking skills
- Proficiency in MS Office (Excel, Word, Outlook)
Location: 10 Colwick Quays Business Park, Road No 2, Colwick, NG4 2JY, Nottingham
Job Type: Full-time (37.5hrs per week)
Salary: Up to £40,000 per annum, depending on experience and skill set
Contract: Permanent
What we offer:
Our benefits package includes a competitive salary, discretionary performance related bonus annually, an initial 3% employer pension contribution, 24 days annual leave. This position is based at our facility at 10 Colwick Quays Business Park, Nottingham, UK.
To apply, please confirm your status of eligibility to work in the UK and send your CV with a covering letter outlining why you feel you would be suitable for this role to info@cellomaticsbio.com.
