Precision Cut Lung Slices & Fibrosis Model

Our precision cut lung slices provide a physiologically relevant ex vivo platform for studying lung fibrosis, tissue remodelling, and therapeutic responses within intact lung architecture. By preserving the native structural complexity of the lung, including epithelial, mesenchymal, and immune cell populations, these models enable researchers to investigate cellular interactions and disease-associated changes in a biologically relevant environment. Precision cut lung slices support the evaluation of fibrotic pathways, extracellular matrix deposition, inflammatory responses, and tissue repair mechanisms while maintaining the three-dimensional organisation of the tissue. This makes them a valuable tool for assessing the efficacy and mechanism of action of novel anti-fibrotic therapies and advancing translational respiratory research.