allergic rhinitis
Respiratory Assays
Allergic Rhinitis
Allergic rhinitis is an inflammatory disorder of the nasal mucosa induced by allergen exposure triggering IgE-mediated inflammation. It can also be associated with co-morbid conditions as Asthma, Atopic Dermatitis & Nasal polyps (Varshney et al., 2015). Our allergic rhinitis research services help scientists investigate the underlying mechanisms of nasal inflammation and allergic responses.
TEER Measurements
Inflammatory mediator expression
Cetirizine and Chlorphenamine maleate suppress pro-inflammatory markers.
RPMI 2650/ hPBMC co-culture monolayers were pre-treated with Cetirizine and Chlorphenamine maleate, stimulated with House Dust Mite Extract (HDME), and inflammatory markers measured by ELISA-based assay (Stats: one-way ANOVA; n as stated; mean ± SEM; *p<0.05, **p<0.01, ***p<0.001).
These allergic rhinitis research capabilities provide valuable insights into immune pathways and support the evaluation of novel therapeutic candidates.
Request a consultation with Cellomatics Biosciences today
Cellomatics offers customised allergic rhinitis research solutions to accelerate drug discovery and translational respiratory research programmes. Our experienced team of in vitro laboratory scientists will work with you to understand your project and provide a bespoke project plan with a professional, flexible service and a fast turnaround time.
To request a consultation where we can discuss your exact requirements, please contact Cellomatics Biosciences.
