allergic rhinitis
Respiratory Assays
Allergic Rhinitis
Allergic rhinitis is an inflammatory disorder of the nasal mucosa induced by allergen exposure triggering IgE-mediated inflammation. It can also be associated with co-morbid conditions as Asthma, Atopic Dermatitis & Nasal polyps (Varshney et al., 2015).
TEER Measurements
Inflammatory mediator expression
Cetirizine and Chlorphenamine maleate suppress pro-inflammatory markers.
RPMI 2650/ hPBMC co-culture monolayers were pre-treated with Cetirizine and Chlorphenamine maleate, stimulated with House Dust Mite Extract (HDME), and inflammatory markers measured by ELISA-based assay (Stats: one-way ANOVA; n as stated; mean ± SEM; *p<0.05, **p<0.01, ***p<0.001)
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