Tight Junction Proteins (TJP)

Tight junction proteins (TJP) are major components of cell to cell adhesion complexes that maintain cell polarity, barrier integrity and regulate diffusion of certain molecules, cell proliferation and differentiation.

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Caco-2 cells were differentiated for 21 days and stained for tight junction proteins such as ZO-1 (purple) and Occludin (orange) along with DAPI (blue- nucleus). The images were captured at 20X magnification using high content imager and the intensities of each fluorescence analysed.

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