Phenotypic Screening
Phenotypic Screening is used to characterise the effect of test molecules by quantifying morphological/phenotypic changes in cell based models. Here at Cellomatics, we have extensive experience in providing and running a wide range of phenotypic screening. Find out more below.
Phagocytosis
Collagen Gel Contraction
Antibody Dependent Cellular Phagocytosis (ADCP)
FAQ's
Phenotypic screening identifies compounds based on their functional effects in a biological system rather than predefined target interactions. This unbiased approach is particularly valuable for discovering novel mechanisms of action and first-in-class therapeutics.
Cellomatics offers a wide range of phenotypic assays, including proliferation, apoptosis, migration, and complex co-culture systems. These assays capture the overall biological response to a compound.Â
High-content imaging and automated liquid handling platforms enable simultaneous measurement of multiple cellular parameters. This provides detailed insight into compound activity and mechanism.
Yes. Assays can be tailored to specific disease areas, including oncology, immunology, and inflammation. Cellomatics frequently uses primary human cells to enhance physiological relevance.
Following hit identification, Cellomatics supports follow-up studies such as pathway analysis and molecular profiling to identify and validate the underlying targets and mechanisms of action.
Request a consultation with Cellomatics Biosciences today
Our experienced team of in vitro laboratory scientists will work with you to understand your phenotypic screening needs and provide a bespoke project plan with a professional, flexible service and a fast turnaround time.
To request a consultation where we can discuss your exact requirements, please contact Cellomatics Biosciences.
