Atopic Dermatitis
Atopic dermatitis (AD) is a chronic, complex allergic inflammatory skin disease that affects 10-20% of the population, characterised by a periodic flare of the symptoms which include red and itchy skin, swollen and cracked. Initial immune response begins with the T helper (Th)2 response and is then shifted to Th1 in the chronic phase.
Atopic Dermatitis - Feasibility study
Primary healthy human keratinocytes were treated with different concentrations of IL-13 along with Poly I:C for 48 hours. Inflammatory markers in the resulting supernatants were analysed using a Human Magnetic Luminex® Assay (n=3, mean±SEM).
Atopic Dermatitis
Primary healthy human keratinocytes were treated with different concentrations of drug along with Poly I:C+ IL-13 (50 ng/ml) for 48 hours. Inflammatory markers in the resulting supernatants were analysed using a Human Magnetic Luminex® Assay (n=3, mean±SEM).
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