NASH: Inducing Fibrosis, Steatosis or Metabolic Stress in vitro

Non-alcoholic steatohepatitis (NASH) is a condition that begins with fat build up around the liver, known as steatosis. The fat build up gets progressively worse and leads to inflammation and fibrosis of the liver. At present, no treatments exist for NASH and lifestyle and nutritional changes are recommended. The absence of available therapies is likely due to the lack of reliable in vitro models for this disease. However, significant progress has been made within this disease area, and Cellomatics is at the forefront of this research with a variety of NASH models available.